王發(fā)選,，醫(yī)學博士、教授,、博士研究生導師,、寧夏醫(yī)科大學青年學術骨干。寧夏醫(yī)科大學公共衛(wèi)生與管理學院職業(yè)衛(wèi)生與環(huán)境衛(wèi)生學系副主任,。自治區(qū)級一流課程《職業(yè)衛(wèi)生與職業(yè)醫(yī)學》負責人,，2021年入選寧夏回族自治區(qū)青年拔尖人才。

從事職業(yè)衛(wèi)生與職業(yè)醫(yī)學教育教學工作16年,，承擔本科生及研究生《職業(yè)衛(wèi)生與職業(yè)醫(yī)學》《醫(yī)學科研方法》《循證醫(yī)學》《圖片處理與論文排版》《職業(yè)環(huán)境危害因素監(jiān)測與評價》等多門課程教學任務,，受到學生一致好評。

科研方面主要從事矽肺發(fā)病及纖維化分子機制研究,，主持國家自然科學基金項目3項,。主持寧夏自然科學基金項目2項，教育廳優(yōu)秀青年教師培育基金項目2項,。參與完成科技部重大專項和多項大型國際合作課題,。發(fā)表高水平科研論文四十余篇。

一,、主持或者參與的科研項目

（1）國家自然科學基金地區(qū)項目,，lncRNA MRAK050699、BC167061競爭結合miR-204-3P靶向TGFBR1調(diào)控EMT過程對矽肺纖維化的影響研究 2021.1-2024.12,，35萬元,，主持；

（2）國家自然科學基金地區(qū)項目,，LncRNA通過調(diào)控TGF/smad3信號通路在矽肺發(fā)生和纖維化中的調(diào)控作用研究,，2017.1-2020.12，41萬元,，主持,；

（3）國家自然科學基金青年基金項目，miR-146a和miR-181b在矽肺發(fā)生和纖維化中的調(diào)節(jié)作用研究,，2013.1-2015.12,，23萬元,，主持；

（4）寧夏自然科學基金重點項目,，LncRNA MRAK052509 吸附miR-204-3p調(diào)控TGF-βRI影響矽肺纖維化的機制研究,，30萬元，主持,；

（5）寧夏重點研發(fā)計劃重點項目,，基于遺傳、環(huán)境復雜網(wǎng)絡的寧夏地區(qū)心腦血管疾病多維預測及防控策略研究,，2021BEG02026,2021.06-2024.05 185萬元,，子課題負責人；

（6）國家重點研發(fā)計劃“精準醫(yī)學”西北區(qū)域自然人群隊列研究 寧夏回漢隊列建設及膳食結構與健康關系研究（2017YFC0907204）,、2017/10-2020/12、269萬元,，主要負責人,。

二、代表性論文：

（1）Faxuan W., Qin Z., Dinglun Z., Tao Z., Xiaohui R., Liqiang Z., Yajia L. Altered microRNAs expression profiling in experimental silicosis rats [J]. The Journal of toxicological sciences, 2012, 37(6): 1207.

（2）Zhang Yang, Wang Faxuan, Lan Yajia, Zhou Dinglun, Ren Xiaohui, Zhao Liqiang, Zhang Qin. Roles of microRNA-146a and microRNA-181b in regulating the secretionof tumor necrosis factor-α and interleukin-1β in silicon dioxide-induced NR8383rat macrophages [J]. Molecular medicine reports, 2015, 12(4): 5587-5593.

（3）Zhang Yang, Wang Faxuan, Zhou Dingzi, Ren Xiaohui, Zhou Dinglun, Gao Xiaosi, Lan Yajia, Zhang Qin, Xie Xiaoqi. Genome-wide analysis of aberrantly expressed microRNAs in bronchoalveolar lavage fluid from patients with silicosis [J]. Industrial Health, 2016, 54(4): 361-369.

(4)Wang Faxuan, Tian Di, Zhao Yi, Li Jiangping, Chen Xiyuan, Zhang Yuhong. High-Density Lipoprotein Cholesterol: A Component of the Metabolic Syndrome with a New Role in Lung Function [J]. Evidence-Based Complementary and Alternative Medicine, 2021, 2021: 6615595.

(5)Neal Bruce, Wu Yangfeng, Feng Xiangxian, Zhang Ruijuan, Zhang Yuhong, Shi Jingpu, Zhang Jianxin, Tian Maoyi, Huang Liping, Li Zhifang, Yu Yan, Zhao Yi, Zhou Bo, Sun Jixin, Liu Yishu, Yin Xuejun, Hao Zhixin, Yu Jie, Li Ka-Chun, Zhang Xinyi, Duan Peifen, Wang Faxuan, Ma Bing, Shi Weiwei, Di Tanna Gian Luca, Stepien Sandrine, Shan Sana, Pearson Sallie-Anne, Li Nicole, Yan Lijing L., Labarthe Darwin, Elliott Paul. Effect of Salt Substitution on Cardiovascular Events and Death [J]. New England Journal of Medicine, 2021, 385(12): 1067-1077.

(6)Wang Faxuan, Wang Binxia, Chen Xiyuan, Liu Wanlu, Wang Guoqi, Li Xiaoxia, Liu Xiuying, Li Nan, Zhang Jiaxing, Yin Ting, Jing Jinyun, Chang Xiaoyu, Jin Yanan, Zhang Yuhong, Zhao Yi. Association Between Blood Pressure and Branched-Chain/Aromatic Amino Acid Excretion Rate in 24-Hour Urine Samples from Elderly Hypertension Patients [J]. Diabetes Metab Syndr Obes, 2021, 14: 3965-3973.

(7)Zhu J, Wang F, Feng X, Li B, Ma L, Zhang J. Family with sequence similarity 13 member A mediates TGF-β1-induced EMT in small airway epithelium of patients with chronic obstructive pulmonary disease. Respir Res. 2021 Jul 1;22(1):192. doi: 10.1186/s12931-021-01783-z. PMID: 34210319; PMCID: PMC8247231.

(8) Wang F. X., Gao F. Y., Liu X., Chen X. Y., Tian D., Tian X. Y., Jiao Z. M., Hou P. Y. Long non-coding RNA expression in silicosis and MRAK050699 function in epithelial-mesenchymal transition [J]. Human & experimental toxicology, 2021, 40(12_suppl): S763-s774.

(9) Tian D., Chen X., Hou P., Zhao Y., Zhao Y., Zhang Y., Li J., Zhang Y., Wang F. Effects of exposure to fine particulate matter on the decline of lung function in rural areas in northwestern China [J]. Environmental science and pollution research international, 2022, 29(10): 14903-14913

(10) Hou Pengyi, Pi Yangyang, Jiao Ziming, et al. Association of Body Composition with Pulmonary Function in Ningxia: The China Northwest Cohort, 2022, 15:3244-3254.